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 Post subject: Synthia
PostPosted: Fri May 21, 2010 9:47 pm  
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Querulous Quidnunc
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http://www.dailymail.co.uk/sciencetech/article-1279988/Artificial-life-created-Craig-Venter--wipe-humanity.html


[youtube]http://www.youtube.com/watch?v=wLKOIHrnk80[/youtube]

Quote:
"You are becoming gods
There's a new master of creation, and it's you!
You've unraveled DNA,
and at the same time, you're cultivating
bacteria strong enough to kill every living thing
D'you think you are ready for that much power?

You lot?
You lot!

Cheeky bastards, you're running around science like kids wi' guns
Creating a new world, while the one you've got is stinking

Go on, 'ands up, 'ands up anyone who thinks you've got it right
Yeah, there's always one.

I can see you.

If you want the position of God, then take the responsibility."



discuss, if you wish.


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 Post subject:
PostPosted: Fri May 21, 2010 10:19 pm  
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Querulous Quidnunc
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whats the old quote? man's reach will always surpass his grasp?


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 Post subject:
PostPosted: Fri May 21, 2010 10:52 pm  
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Querulous Quidnunc
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Usdk wrote:
whats the old quote? man's reach will always surpass his grasp?


you're quite wise.


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 Post subject:
PostPosted: Sat May 22, 2010 4:42 pm  
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Very significant, it is forseeable for humans to be engineering more complex oganisms for various purposes, possibilities are endless. Especially when one considers the fact that scientists have made a ribsoome (the thing that reads RNA (comes from dna) and builds the protiens, that instead of reading 3 codons of DNA, will read four at a time. What that means is that instead of the 3 at a time, which limits DNA coding to the 20 naturally occuring amino acids, it now opens the door for use of synthetic amino acids. With a ribosome that reads 4 at a time, thats 256 possible codes (iirc). With synthetic amino acids, the resulting protiens can be made to do almost anything. Talking things in the way of kevlar-like skin and super strength. Many super hero qualities could be engineered out of that.

Ofcourse making humans with the ability to lift 10 tons is a far way off, but the impications remain nonetheless. Will be interesting to see what comes out of this in the next 10-20 years.


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 Post subject:
PostPosted: Sat May 22, 2010 4:49 pm  
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It's not significant.

The title is misleading. They didn't create life. They hijacked an existing organism and put new DNA in it. It's nothing more than what's been done for years with retroviruses.

Scientists still do not actually understand how the proteome interacts with "junk" DNA to organize its content into a viable lifeform, which is central to actually creating life. The answer to that question is as far off as ever and we may not have even a partial answer for thousands of years because scientists have no idea how to go about attacking the mystery.

There would also be the vastly more challenging task of actually engineering and animating an organism from scratch. This is a task even greater than reanimating the dead. We can't even cure SIDS or other forms of death that occur when the body ceases to live even though it is physically intact. This is the proverbial "touch of life" as seen in the Sistine Chapel - turning a collection of organelles into a functioning organism.


Aestu of Bleeding Hollow...

Nihilism is a copout.
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 Post subject:
PostPosted: Sat May 22, 2010 4:59 pm  
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Then what exactly did they do? The way that I've heard it is that they made their own chromosome, took an empty cell with nothing in it. Injected the chromosome into the cell, fed it certain chemicals and it reproduced.

They created life, because iirc from my grade 9 science class, the three requirements for something to be considered alive is that it:
Eats (takes in energy from the environment in some way)
Craps (waste from byproducts of breaking down food into energy)
Replication.

They took an empty cell that was in all manner of speaking, dead, made their chromosome, put it in there and then the cell did all of the 3 above. Hence they created life.


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 Post subject:
PostPosted: Sat May 22, 2010 5:03 pm  
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http://cmapsnasacmex.ihmc.us/servlet/SB ... me=htmljpg

Just found this, think it may prove useful for something in here...


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 Post subject:
PostPosted: Sat May 22, 2010 5:18 pm  
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quadtard wrote:
Then what exactly did they do? The way that I've heard it is that they made their own chromosome, took an empty cell with nothing in it. Injected the chromosome into the cell, fed it certain chemicals and it reproduced.

They created life, because iirc from my grade 9 science class, the three requirements for something to be considered alive is that it:
Eats (takes in energy from the environment in some way)
Craps (waste from byproducts of breaking down food into energy)
Replication.

They took an empty cell that was in all manner of speaking, dead, made their chromosome, put it in there and then the cell did all of the 3 above. Hence they created life.


The cell was alive. It was a pre-existing lifeform. They simply reprogrammed it.

It wasn't "empty". They removed the chromosomes from the nucleus and put their own in. There's ubiquitous lab machines you can buy - pretty cheaply too - that will print out a piece of DNA with the codes you type in, and it's easy enough to simply transcribe existing codes.

To actually build a cell - to create life itself - would be a vastly more challenging task. And that's just one cell, that may not even achieve homeostasis which is a necessary condition of life. Humans have never succeeded in creating anything homeostatic.


Aestu of Bleeding Hollow...

Nihilism is a copout.
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 Post subject:
PostPosted: Sat May 22, 2010 7:37 pm  
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Well then in that case, why is this getting such fanfare and attention if its no big deal? Seems to be getting an awful lot of attention for something that you dismiss as simple and meaningless.


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 Post subject:
PostPosted: Sat May 22, 2010 8:15 pm  
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quadtard wrote:
Well then in that case, why is this getting such fanfare and attention if its no big deal? Seems to be getting an awful lot of attention for something that you dismiss as simple and meaningless.


It got a lot of fanfare because a) the scientists involved (ie. Craig Venter) are very good at self-promotion, and b) reporters love the "scientists create life" angle. This was a big technical advance in terms of synthesizing an entire genome and getting it to function in a cell, but they copied an existing genome and inserted it into an existing cell - not much actual creation going on.

There are more advanced projects going on, and we will probably see a lot of progress in the next few years. The same group is working on reducing one of these Mycoplasma genomes to the minimum number of genes needed to survive, which would be closer to being an actual synthetic lifeform. It's not a huge conceptual leap to start adding genes from other organisms to do things like break down cellulose for biofuels, which is the ultimate goal for Venter.
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 Post subject:
PostPosted: Sat May 22, 2010 8:30 pm  
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Quote:
It's not a huge conceptual leap to start adding genes from other organisms to do things like break down cellulose for biofuels, which is the ultimate goal for Venter.


which would net him a shitload of money


Verily, I have often laughed at weaklings who thought themselves proud because they had no claws.
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 Post subject:
PostPosted: Sat May 22, 2010 8:35 pm  
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Dotzilla wrote:
Quote:
It's not a huge conceptual leap to start adding genes from other organisms to do things like break down cellulose for biofuels, which is the ultimate goal for Venter.


which would net him a shitload of money


I believe he's already a billionaire, but yeah he would be minting money if it works and if it's patentable.
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 Post subject:
PostPosted: Sat May 22, 2010 8:36 pm  
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Dotzilla wrote:
which would net him a shitload of money


So he wants to build an energy empire on the backs of enslaved micro-organisms?


Aestu of Bleeding Hollow...

Nihilism is a copout.
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 Post subject:
PostPosted: Sun May 23, 2010 1:36 am  
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Dotzilla wrote:
Quote:
It's not a huge conceptual leap to start adding genes from other organisms to do things like break down cellulose for biofuels, which is the ultimate goal for Venter.


which would net him a shitload of money


I have a far more clever idea for a new fuel system, but I'd need an engineer, a biochemist, and a genetic researcher to get it to work, and it'd probably need a lot of work to make it efficient.

On second thought, forget I said anything.

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 Post subject:
PostPosted: Sun May 23, 2010 1:56 am  
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So after reading this article and looking at what people think....I can only come to one conclusion.

HOLY SWEET JESUS TITTIES CINNAMON WHY DOES EVERYONE THINK THIS SHIT WILL CAUSE "I AM LEGEND" TO OCCUR.

The entire shit is based off unsubstantial evidence used to draw hasty conclusions about shit that we don't even know about, all tied up in a slippery slope argument.

Far as I'm aware: Scientist, go nutz with making what ever crazy shit you can achieve. So they say that it could end the world and such, what exactly is that statement based off? Some psychic reading from some outdated hand reader who's saving up to buy another toaster oven for her HOT POCKETS?

Point being, everyone needs to just chill the fuck out when it comes to everytime someone seems to test the limits of science as we know it. No one knows whats going to happen next, these synthetic life forms could take over the world, be used as bio weapons or just be used to i dunno, cure diseases and advance medical health care.

Summary: HOLY PICKLED BOLOGNA LOAF CHILL OUT, YOU HAVE NO IDEA WHAT THE FUTURE WILL BE LIKE SO STOP THINKING YOU GET TO BE WILL SMITH IN YOUR OWN REAL LIFE RENDITION OF "I AM LEGEND"


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